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Molson Medical Informatics Sampler


A Media Sampler showcasing illustrations, animations and build overlays designed
 for the enhanced version of the McGill Basis of Medicine Notes. 


Introduction
 
The McGill Molson Medical Informatics Project is committed to enhancing medical teaching and learning through the integration of technology, art and pedagogy.

This conversion of teaching material to electronic format has required multiple iterations. The following link demonstrates the evolution of this process from the perspective of the development of multimedia images:  Before and After

 
Illustrations
 
  • Static illustrations employ colour and design  to help elucidate concepts or clarify anatomy. 
     

 

From Dr. K. Cianflone:  Lecture 60. Amino Acid Metabolism 

The Alanine released by muscle, kidneys and the gut ends up in the liver, which is the major site of gluconeogenesis and urea synthesis. Of the amino acids taken up by the liver from the circulation, over 50% is in the form of Alanine. Alanine is thus the major glucogenic precursor.

 
 

 

 

  

 

From Dr. D. Eidelman:  Lecture 12. Pulmonary Ventilation

The pulmonary airway tree begins with the trachea which consists of a series of cartilage horseshoes connected together by soft tissue.

The trachea bifurcates at the carina, behind the sternum, to produce the two mainstem bronchi. These in turn divide into the lobar bronchi (2 on the left, 3 on the right). The lobar bronchi again bifurcate, and so on for about 23 generations. The first 16 or so of these generations act merely as conduits for passage of gas, and together constitute the conducting zone. Beyond the 16th generation, alveoli start to appear in the airway walls, becoming more numerous until the process terminates in an acinus consisting of a large collection of alveoli.
 

 

 

  

From Dr. M. McKee:  Lecture 26. Histology of Respiratory System 3. 

Respiratory Bronchiole

Alveolar ducts are small ducts leading from the respiratory bronchioles to the alveolar sacs.

The respiratory bronchiole epithelium consists of ciliated cuboidal cells and clara cells.

 

 

 

  

From Dr. M. McKee: Lecture 21.  Bone Growth and Remodelling.

The structure of adult bone.
 

 

 

  

From Dr. G. Mandl:  Lecture 28. The Autonomic Nervous System

The precise location of the autonomic ganglia differs for sympathetic and parasympathetic divisions. 

For the sympathetic system, synaptic contact between pre- and post-ganglionic neurons frequently takes place within the para-vertebral ganglia located in pairs right next to (para = near, beside) the spinal cord segments, forming neural chains that run up and down both sides of the spinal cord (sympathetic trunks).

 

 


 

  
From Dr. H. Zingg:  Lecture 61.  Hormones of the Adrenal Cortex

The adrenals are located atop the kidneys. The cortex contains three zones: zona glomerulosa, fasciculata and reticularis. Specific steroids are produced in the three zone. It is thought that the arrangement of blood flow from outer cortex to inner medulla is involved in determining the relevant enzyme activities in each zone.
 

 

 

  
 

From Dr. D. Osmond:  Minimed Community Outreach Program.
Anatomy of the Hand

Dissection of the right palm and wrist showing muscles, tendons, bones, nerves and arteries.

 
 

 

 

  

Simple Frame by Frame Animations

 

  • Button-activated animations allow lecturer and student to study and review complex dynamic principles 

 

 
From Dr. A Shrier:  Lecture 29. Introduction and Basic Cardiac Electrophysiology

The specialized electrical system of the heart consists of the sinoatrial node, the atrioventricular node, the bundle of His, the left and right bundle branches, and the Purkinje fibre network.

 

 

 

  
 

 

From Dr. G. Mandl:  Lecture 7. Muscle Structure and Function.  

Calcium is a key "player" in muscle contraction.

 

 

 

 

  
From Dr. N. Beauchemin:  Lecture 6. DNA Replication.  

Molecular cloning - inserting a DNA fragment into an appropriate vector.  Cloning is accomplished using compatible restriction sites in both the incoming fragment and the recipient vector.  The incoming fragment will be subjected to "ligation" (sewing both fragments up).

 

 

 

  
Builds
 
  • In a media element we call a "build", a complex image is divided into various layers in order to isolate certain elements or aspects of the image at a time.  
     

 
From Dr. G. Mandl: 
Lecture 7.  Muscle Structure and Function.  

Regulation of contraction by calcium

 

A. Receptor Mechanisms
 B. Membrane potential - dependent channels
 C. Ca++ released
 D. Ca++ removed

Overview
 

 

 

 

  
From M. Ludwig:  Lecture 8. Lung Dynamics

Flow volumes in the lung in normal and diseased states

 
Normal
 Bronchitis
 Emphysema
 Pulmonary Fibrosis
 Chest Wall Disease

Overview

 

 

 

From Dr. N. Beauchemin:  Lecture 7:  DNA Repair.
 

Biochemical addition of an incoming nucleotide to a growing chain of DNA. 

Zooming in shows a macromolecular view of the same process together with the enzyme catalyzing the reaction.
 

 

 

  
From C. Chalk:
Lecture 72.  Nerve Conduction Studies
and Electromyography

By assessing the size, duration, and firing pattern
of the motor unit potentials in a muscle, the 
neurologist can evaluate whether the motor units in
that muscle are normal or abnormal.

 
Normal 
Muscle Disease 
Nerve Disease
 

 

 

 

  

 

From N. Beauchemin:
Lecture 4.  Chemical Components of Cells - DNA

DNA fragments of various lengths can be separated in a number of matrices  by electrophoresis. 

A Southern blot is used to detect interesting fragments hybridizing with a particular probe.  

Step 1
 Step 2
 Step 3
 Step 4
 Step 5

Overview

 

 

 

 

  

From Dr. D. Osmond:  Minimed:  Community Outreach Program.

The Visible Human

Layered representation of human systems

 
 

 

 

  
  Complex Module
 

 

  

Click here to open the Flash Animation

(N.B.  This is a 5 MEG File)

 

From Dr. D. Osmond:  Minimed:  Community Outreach Program.

The Hand

Module integrating video and imagery explaining hand and arm muscle anatomy for several key movements.